The BP COG study is a National Institutes of Health (NIH) / National Institute of Neurological Disorders and Stroke (NINDS)-funded R01 study that aims to determine the effect of high blood pressure over the life course on the risk of cognitive impairment and dementia in Blacks, Hispanics, and Whites, and to estimate the potential impact of optimal high blood pressure treatment intensity to reduce racial/ethnic disparities in cognitive impairment and dementia.
The MCI DeM study is a National Institutes of Health (NIH) / National Institute on Aging (NIA)-funded R01 study that aims to compare the quality of cardiovascular disease care in adults with and without mild cognitive impairment (MCI) and to determine the influence of MCI on patient preferences and physician recommendations for heart attack and stroke treatment.
The STROKE COG study is an NIH-funded R01 study that aims to advance the understanding of post-stroke dementia and how post-stroke blood pressure, glucose, and lipid levels independently contribute to post-stroke dementia risk.
JAMA Neurology: Association Between Blood Pressure and Later-Life Cognition Among Black and White Individuals
In this pooled cohort analysis of 19, 378 participants, black individuals, compared with white individuals, had significantly faster declines in global cognition. Differences between black and white individuals in global cognition decline were no longer statistically significant after adjusting for cumulative mean systolic blood pressure.
Researchers target blood pressure in quest to understand, reduce racial disparities in dementia development.
Incident stroke was associated with an acute decline in cognitive function and also accelerated and persistent cognitive decline over 6 years.