The BP COG study is a National Institutes of Health (NIH) / National Institute of Neurological Disorders and Stroke (NINDS)-funded R01 study that aims to determine the effect of high blood pressure over the life course on the risk of cognitive impairment and dementia in Blacks, Hispanics, and Whites, and to estimate the potential impact of optimal high blood pressure treatment intensity to reduce racial/ethnic disparities in cognitive impairment and dementia.
The MCI DeM study is a National Institutes of Health (NIH) / National Institute on Aging (NIA)-funded R01 study that aims to compare the quality of cardiovascular disease care in adults with and without mild cognitive impairment (MCI) and to determine the influence of MCI on patient preferences and physician recommendations for heart attack and stroke treatment.
We aim to identify risk and resilience factors that impact cognitive health, and to optimize precision in assessment of cognition through consideration of factors (e.g., linguistic, cultural, and educational experiences) that may impact the cognitive assessment process.
We aim to improve precision in harmonization of cognitive data across studies through use of detailed documentation and review procedures to ensure comparability of cognitive data.
The Predictors and Long-Term Trajectory of Poststroke Cognitive Decline study is a completed NIH/NIA-funded study (K23AG040278; principal investigator, Deborah Levine) that aimed to determine the predictors and long-term trajectory of cognitive decline after stroke.
This study will: 1) extend the data collection of Reach Out, our ongoing clinical trial to explore innovative mobile health approaches of measuring cognition and blood pressure among our predominately work-age African American participants; and 2) estimate the prevalence of dementia among hypertensive Emergency Department patients to better understand Emergency Department patients’ needs.
This phase III, open-label, blinded-endpoint assessment, multicenter, randomized, controlled trial will test the effect of treatment of obstructive sleep apnea with CPAP after acute ischemic stroke reduces mortality and cardiovascular events and improves stroke recovery.
The Center to Accelerate Population Research in Alzheimer’s (CAPRA) is focused on science that informs government and healthcare organization actions to address the negative impacts of dementia on health and financial well being of individuals and the population.
This study will determine the relationship of educational attainment, cardiovascular health, and ambient air pollution to the risk for cognitive decline and dementia in a nationally-representative sample of adults in India using new data from the Longitudinal Aging Study in India (LASI).
This study will conduct a follow-up to the 2016 Health and Retirement Study (HRS) Harmonized Cognitive Assessment Protocol (HCAP) sub-study.